Safety profiles of adalimumab, etanercept and infliximab: a pharmacovigilance study using a measure of disproportionality in a database of spontaneously reported adverse events.

Safety profiles of adalimumab, etanercept and infliximab: a pharmacovigilance study using a measure of disproportionality in a database of spontaneously reported adverse events.

Safety profiles of adalimumab, etanercept and infliximab: a pharmacovigilance study using a measure of disproportionality in a database of spontaneously reported adverse events.

Diogo Mendes, Carlos Alves, Francisco Batel Marques

Journal of Clinical Pharmacy and Therapeutics 2014. DOI: 10.1111/jcpt.12148

2014

Two-dimensional segmentation of the retinal vascular network from optical coherence tomography.

Two-dimensional segmentation of the retinal vascular network from optical coherence tomography.

Two-dimensional segmentation of the retinal vascular network from optical coherence tomography.

Rodrigues P., Guimarães P., Santos T., Simão S., Miranda T., Serranho P., Bernardes R.

J Biomed Opt, 2013, 18(12), 126011. doi:10.1117/1.JBO.18.12.126011

2013
http://biomedicaloptics.spiedigitallibrary.org/article.aspx?articleid=1790514%20&journalid=93#Data

Fully-Automatic Multimodal Co-Registration of Retinal Fundus Images.

Fully-Automatic Multimodal Co-Registration of Retinal Fundus Images.

Fully-Automatic Multimodal Co-Registration of Retinal Fundus Images.

Bernardes R., Guimarães P., Rodrigues P., Serranho P.

Yuan-Ting Zhang. The International Conference on Health Informatics. ed. Cham: Springer International Publishing, 2014, 42, 248-251. doi:10.1007/978-3-319-03005-0_63

2014

Neuropeptide Y receptors Y1 and Y2 are present in neurons and glial cells in rat retinal cells in culture.

Neuropeptide Y receptors Y1 and Y2 are present in neurons and glial cells in rat retinal cells in culture.

Neuropeptide Y receptors Y1 and Y2 are present in neurons and glial cells in rat retinal cells in culture.

Santos-Carvalho A., Aveleira C., Elvas F., Ambrósio A., Cavadas C.

Invest Ophthalmol Vis Sci., 2013, 54(1):429-43. doi: 10.1167/iovs.12-10776.

2013

Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate.

Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate.

Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate.

Santos-Carvalho A., Elvas F., Álvaro A., Ambrósio A., Cavadas C.

Cell Death and Disease, 2013, 4:e636. doi:10.1038/cddis.2013.160

2013

Numerical solution of time-dependent Maxwell´s equations for modeling scattered electromagnetic wave´s propagation.

Numerical solution of time-dependent Maxwell´s equations for modeling scattered electromagnetic wave´s propagation.

Numerical solution of time-dependent Maxwell´s equations for modeling scattered electromagnetic wave´s propagation.

Araújo A., Barbeiro S., Pinto L., Caramelo F., Correia A., Morgado M., Serranho P., Silva A., Bernardes R.

Proceedings of the 13th International Conference on Computational and Mathematical Methods in Science and Engineering, CMMSE, 2013. ISBN:978-84-616-2723-3

2013

Development of an Optical Coherence Tomograph for Small Animal Retinal Imaging.

Development of an Optical Coherence Tomograph for Small Animal Retinal Imaging.

Development of an Optical Coherence Tomograph for Small Animal Retinal Imaging.

Silva S., Domingues J., Agnelo J., Morgado A., Bernardes R.

Roa Romero. XIII Mediterranean Conference on Medical and Biological Engineering and Computing 2013. ed. Cham: Springer International Publishing, 2014, 41, 419-422. doi:10.1007/978-3-319-00846-2_104

2014

Explicit and Semi-implicit Complex-Diffusion Schemes for Optical Coherence Tomography Despeckling.

Explicit and Semi-implicit Complex-Diffusion Schemes for Optical Coherence Tomography Despeckling.

Explicit and Semi-implicit Complex-Diffusion Schemes for Optical Coherence Tomography Despeckling.

Rodrigues P., Guimarães P., Araújo A., Barbeiro S., Bernardes R., Serranho P.

in Image Analysis and Recognition, ser. Lecture Notes in Computer Science, M. Kamel and A. Campilho, Eds. Springer Berlin Heidelberg, 2013, 7950, pp. 282-289. doi 10.1007/978-3-642-39094-4_32

2013

Development of an Optical Coherence Tomograph (OCT) for Small Animal Retinal Imaging.

Development of an Optical Coherence Tomograph (OCT) for Small Animal Retinal Imaging.

Development of an Optical Coherence Tomograph (OCT) for Small Animal Retinal Imaging.

Silva S., Domingues J., Agnelo J., Oliveira J., Morgado M., Bernardes R.

IEEE 3rd Portuguese BioEngineering Meeting, February 20-23, Braga, Portugal, 2013, 1-4. doi: 10.1109/ENBENG.2013.6518404

2013

Prospective Evaluation of an Automated System to reduce Human Grading Burden in a Diabetic Retinopathy Screening Program

Prospective Evaluation of an Automated System to reduce Human Grading Burden in a Diabetic Retinopathy Screening Program

Prospective Evaluation of an Automated System to reduce Human Grading Burden in a Diabetic Retinopathy Screening Program

Neves CA, Oliveira CM, Ribeiro ML, Ferreira HJ, Cunha-Vaz JG

Invest Ophthalmol Vis Sci 2012:53:E-Abstract 2890.

2012

Iatrogenia grave desconhecida, notificações e notificadores: resultados da actividade da Unidade de Farmacovigilância do Centro

Iatrogenia grave desconhecida, notificações e notificadores: resultados da actividade da Unidade de Farmacovigilância do Centro

Iatrogenia grave desconhecida, notificações e notificadores: resultados da actividade da Unidade de Farmacovigilância do Centro

Diogo Mendes, Carlos Alves, Francisco Batel Marques

Rev Port Med Geral Fam 2012;28:34-40

2012

Implemented Data Mining and Signal Management Systems on Spontaneous Reporting Systems’ Databases and their Availability to the Scientific Community – A Systematic Review

Implemented Data Mining and Signal Management Systems on Spontaneous Reporting Systems’ Databases and their Availability to the Scientific Community – A Systematic Review

Implemented Data Mining and Signal Management Systems on Spontaneous Reporting Systems’ Databases and their Availability to the Scientific Community – A Systematic Review

Lima LMAV, Craveiro N, Dias PGP, and Batel Marques FJ

Curr Drug Saf. 2012;7(2):170-5

2012

A meta-analysis of serious adverse events reported with exenatide and liraglutide: Acute pancreatitis and cancer

A meta-analysis of serious adverse events reported with exenatide and liraglutide: Acute pancreatitis and cancer

A meta-analysis of serious adverse events reported with exenatide and liraglutide: Acute pancreatitis and cancer

Carlos Alves, Francisco Batel Marques, Ana Filipa Macedo

Diabetes Res Clin Pract 2012;98(2):271-84

2012

Validation of the automatic identification of eyes with diabetic retinopathy by OCT.

Validation of the automatic identification of eyes with diabetic retinopathy by OCT.

Validation of the automatic identification of eyes with diabetic retinopathy by OCT.

Santos T., Ribeiro L., Lobo C., Bernardes R., Serranho P.

IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG), 2012

2012
http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6331373

3D Adaptive Nonlinear Complex-Diffusion Despeckling Filter.

3D Adaptive Nonlinear Complex-Diffusion Despeckling Filter.

3D Adaptive Nonlinear Complex-Diffusion Despeckling Filter.

Rodrigues P., Bernardes R.

This work aims to improve the process of speckle noise reduction while preserving edges and other relevant features through filter expansion from 2D to 3D. Despeckling is very important for data visual inspection and as a preprocessing step for other algorithms, as they are usually notably influenced by speckle noise. To that intent, a 3D approach is proposed for the adaptive complex-diffusion filter. This 3D iterative filter was applied to spectral-domain optical coherence tomography medical imaging volumes of the human retina and a quantitative evaluation of the results was performed to allow a demonstration of the better performance of the 3D over the 2D filtering and to choose the best total diffusion time. In addition, we propose a fast graphical processing unit parallel implementation so that the filter can be used in a clinical setting.

IEEE Trans Med Imaging, 2012, 31(12), 2205-2212.

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2012
http://doi.org/10.1109/TMI.2012.2211609