Multimodal Macula Mapping: study for rigid, perspective and deformable image registration.

Baptista P., Bernardes R., Ferreira J., Dias J., Cunha-Vaz J.

In this work, thirteen image-pairs, composed of a color fundus photograph and a scanning laser ophthalmoscope fluorescein angiography (SLO.FA), were registered by rigid, non-rigid and deformable image registration procedures to assess the need for deformable image registration methods when using SLO.FA modalities. Each registration was quantitatively assessed by three different metrics that showed improved performance of the deformable approach. Moreover, the computed deformation grids demonstrated the infeasibility of global transformation approaches to deal with saccadics, as expected. Also, in the registration of medical images, some knowledge of the acquisition mode and its particularities was shown necessary to successfully achieve good registration results with a reduced search space for the parameters involved.

IFMBE Proceedings, Vol. 11. Prague: IFMBE, 2005. ISSN 1727-1983. – Proceedings of the 3rd European Medical & Biological Engineering Conference – EMBEC´05. Prague, Czech Republic, 20-25.11.2005. ID of full-paper followed by page – from 1867-1 to 1867-6.

2005