Distortion free registration between multifocal ERG and retinal leakage analyzer.

Bernardes R., Ferreira J., Baptista P., Sebastião A., Dias J., Cunha-Vaz J.

The aim of the present work is the registration of two functional imaging modalities while simultaneously correcting for the intrinsic distortions present on both. Two recently introduced imaging modalities are used in this work, one that measures the retina response to blue light stimuli and another that measures the blood-retinal barrier function. A deformable registration procedure was developed, comprising a model for saccadic eye movements which allows for an important reduction in the number of parameters which need to be estimated. Finally, simultaneous correction for the intrinsic distortions was achieved through resorting to an additional imaging modality, thus resulting in practice in the registration of three different modalities, the former two of the functional type and the latter of the morphological type.

IFMBE Proceedings, Vol. 11. Prague: IFMBE, 2005. ISSN 1727-1983. – Proceedings of the 3rd European Medical & Biological Engineering Conference – EMBEC´05. Prague, Czech Republic, November 20-25, 2005, pages 1868-1 to 1868-6.

2005