Challenges, facilitators and barriers to screening study participants in early disease stages-experience from the MACUSTAR study

Terheyden JH, Behning C, Lüning A, Wintergerst L, Basile PG, Tavares D, Melício BA, Leal S, Weissgerber G, Luhmann UFO, Crabb DP,Tufail A, Hoyng CB, Berger M, Schmid M, Silva R , Martinho CV, Cunha-Vaz J, Holz FG, Finger RP, MACUSTAR consortium

BMC Med Res Methodol. 2021 Mar 17;21(1):54. doi: 10.1186/s12874-021-01243-8.

2021

Current management of patients with RPE65 mutation-associated inherited retinal degenerations (IRDs) in Europe. Results of a multinational survey by the European Vision Institute Clinical Research Network EVICR.net

Lorenz B, Tavares J, van den Born LI, Marques JP, Scholl HPN, The EVICR.net Group

2021 Mar 8. doi: 10.1159/00051568

2021

Current management of Inherited Retinal Degenerations (IRD) patients in Europe. Results of a multinational survey by the European Vision Institute Clinical Research Network EVICR.net

Lorenz B, Tavares J, van den Born LI, Marques JP, Scholl HPN.

Ophthalmic Res. 2021 Jan 19. doi: 10.1159/000514540

2021

 

Development of a Genotype Assay for Age-Related Macular Degeneration: The EYE-RISK Consortium

de Breuk A, Acar IE, Kersten E, Schijvenaars MMVAP, Colijn JM, Haer-Wigman L, Bakker B, de Jong S, Meester-Smoor MA, Timo Verzijden, Missotten TOAR, Monés J, Biarnés M, Pauleikhoff D, Hense HW, Silva R, Nunes S, Melo JB, Fauser S, Hoyng CB, Ueffing M, Coenen MJH, Klaver CCW, den Hollander AI, EYE-RISK Consortium.

Ophthalmology. 2020 Jul 24;S0161-6420(20)30725-9. doi: 10.1016/j.ophtha.2020.07.037.

https://reader.elsevier.com/reader/sd/pii/S0161642020307259?token=7C3855F4931D40A7D8232C4B1BE25B807B16462FA80BF01A4237E6905759EF9DBBC9F32B3AB5F0B94D301274E08CA61C

Use of composite endpoints in early and intermediate age-related macular degeneration clinical trials – state-of-the-art and future directions

Terheyden J.H. Schmitz-Valckenberg S. Crabb D. Dunbar H. Luhmann U. Behning C. Schmid M. Pires I. Cunha-Vaz J. Tufail A. Weissgerber G. Leal S. Holz F.G. Finger R.P.

Ophthalmologica. 2020 Dec 7. doi: 10.1159/000513591.

https://www.karger.com/Article/Abstract/513591

Phenotypic And Genetic Variations Between Asian And Caucasian Polypoidal Choroidal Vasculopathy Eyes.

Jordan-Yu, JMN, Teo K, Fan Q, Gan JC, Leopoldo AK, Nunes S, Farinha C. Barreto P, Melo JB, Carreira I, Murta JN, Silva R, Cheung CMG

Br. J. Ophthalmol. 317537, (2020). doi: 10.1136/bjophthalmol-2020-317537

https://bjo.bmj.com/content/early/2020/10/13/bjophthalmol-2020-317537.long#

Clinical study protocol for a low-interventional study in intermediate age-related macular degeneration developing novel clinical endpoints for interventional clinical trials with a regulatory and patient access intention-MACUSTAR.

Jan H Terheyden , Frank G Holz , Steffen Schmitz-Valckenberg , Anna Lüning , Matthias Schmid , Gary S Rubin, Hannah Dunbar, Adnan Tufail , David P Crabb, Alison Binns , Clara I Sánchez, Carel Hoyng 6, Philippe Margaron, Nadia Zakaria, Mary Durbin, Ulrich Luhmann , Parisa Zamiri , José Cunha-Vaz, Cecília Martinho, Sergio Leal , Robert P Finger , MACUSTAR consortium

Trials . 2020 Jul 18;21(1):659. doi: 10.1186/s13063-020-04595-6.

2020

Safety Assessment of an A‐Scan Ultrasonic System for Ophthalmic Use.

Petrella L.; Fernandes P; Santos M; Caixinha M.; Nunes S.; Pinto C.; Morgado M.; Santos J.; Perdigão F.; Gomes M.

J Ultrasound Med 2020; 9999:1–8 doi:10.1002/jum.15323

2020

Characterization of disease progression in the initial stages of retinopathy in diabetes type 2. A two-year longitudinal study.

Inês P. Marques, Dalila Alves, Torcato Santos, Luís Mendes, Conceição Lobo, Ana Rita Santos, Mary Durbin, José Cunha-Vaz

Invest Ophthalmol Vis Sci. 2020 Mar 9;61(3):20. doi: 10.1167/iovs.61.3.20.

2020

Unmet Medical Needs in Ophthalmic Research: An EVI Consensus Roadmap. 2019-2025. Diabetic Retinopathy

Cunha-Vaz J

Ophthalmic Res. 2019;62(3):123-133. doi: 10.1159/000501374. Epub 2019 Aug 5.

2019