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Past Projects


Coimbra Coordinating Centre for Clinical Research

Clinical evaluation of noninvasive OCT Angiography using a Zeiss OCT Prototype to replace fluorescein angiography. (Dispositivo Médico Zeiss OCTA) [more info]

Prediction of response to Certolizumab Pegol treatment by functional MRI of the brain. A multi-center, randomized double-blind controlled study (PreCePra). 2013-000337-13 [more info]

A non-randomised, open-label, multicenter phase 4 pilot study on the effect and safety of Iluvien® in chronic diabetic macular edema patients considered insufficiently responsive to available therapies with or without intravitreal corticosteroid therapy (RESPOND). Protocol 4C-2014-06 [more info]

Validation of a Predictive Model to Estimate the Risk of Conversion to clinically Significant Macular Edema and/or Vision Loss in Mild Nonproliferative Diabetic Retinopathy in Diabetes Type 2 (CPM). Protocol CNTM/330 [more info]

Observational Study of Type 2 diabetic subjects to validate Diabetic Retinopathy Phenotypes (Phenotyping DR). CNTM018A [more info]

Prevention of Macular Edema After Cataract Surgery (PREMED). Protocol NL-42463.068.12 [more info]

European young investigators network for Usher syndrome: Colletion of clinical data of European USHER patients to standardize and improve diagnosis, to decipher the molecular pathogenesis and to evaluate the therapy strategies for Usher Syndrome. (USHER). Protocol P13-02 [more info]

European Leber’s Hereditary Optic Neuropathy Disease Registry Protocol (LHON). Protocol SNT-IV-004. [more info]

A Collaborative Retrospective Trial on the Efficacy and Safety of intravitreal dexamethasone implant (Ozurdex) in patients with Diabetic Macular Edema (DME). THE EUROPEAN DME REGISTRAR STUDY (ARTES). Protocol ECR-RET-2014-07. [more info]

Characterization of Eyes with Diabetic Macular Edema that show different Treatment Response to Intravitreal anti-VEGF (CHARTRES). Protocol 4C-2013-05 [more info]

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