Sandrina Nunes Director 4C 4C - Coimbra Coordinating Centre for Clinical Research
CORC - Coimbra Ophthalmology Reading Centre

 

Personal data

Participation in research projects

• POLARIS - A Prospective non-interventional study to assess the effectiveness of existing anti-vascuLar endothelial growth factor (Anti-VEGF) treatment regimens in patients with diabetic macular edema (DME) with central involvement. [more info]
• Retinal Disease Screening System (RDSS) [more info]
• Correlation phenotype/genotype in diabetic retinopathy (Protocol CEC/120) [more info]
• Evaluation of blood-retinal barrier functional alterations by optical coherence tomography (PTDC/SAU-BEB/103151/2008) [more info]
• Validation of a predictive model to estimate the risk of conversion to clinically significant macular edema and/or vision loss in mild nonproliferative retinopathy in diabetes type 2 [more info]
• Structure-function imaging for quantitive phenotyping or retinal degenerations [more info]
• Characterization of the mechanisms of resolution of diabetic macular edema after photocoagulation treatment with laser [more info]

Publications

• Simao S.N., Nunes S., Vilhena N., Cachulo M.L., Faria de Abreu J., Cunha-Vaz J., Silva R. Validation of Retmarker AMD for Quantification of Early Age-Related Maculopathy Features. [more info]
• Santos A.R., Cachulo M.L., Fonseca P., Nunes S., Bernardes R., Cunha-Vaz J., Silva R. Risk Factors for the Development of Choroidal Neovascularization in the Fellow Eye of Patients with Age Related Macular Degeneration - A Three Year Follow-up Study. [more info]
• Coutinho A.M., Silva R.M., Nunes S.G., Cachulo M.L., Figueira J.P., Murta J.N. Photodynamic therapy in highly myopic eyes with choroidal neovascularization: 5 years of follow-up. [more info]
• Silva R., Cachulo M., Fonseca P., Bernardes R., Nunes S., Vilhena N. & Faria de Abreu J. Age-related macular degeneration and risk factors for the development of choroidal neovascularisation in the fellow eye: a 3-year follow-up study [more info]
• Nunes S., Pereira I., Santos A., Bernardes R., Cunha-Vaz J. Retinal thickness with HD-OCT is not a surrogate outcome for visual acuity changes in diabetic macular edema. [more info]
• Silva MF, Mateus C., Reis A., Nunes S., Fonseca P., Castelo-Branco M. Asymmetry of Visual Sensory Mechanisms: Electrophysiological, Structural, and Psychophysical Evidences [more info]
• Nunes S., Pereira I., Santos A., Bernardes R., Cunha-Vaz J. Central retinal thickness measured with HD-OCT shows a weak correlation with visual acuity in eyes with CSME. [more info]
• Bernardes R., Nunes S., Pereira I., Lobo C., Cunha-Vaz J. Semi-automated assessment of microaneurysm formation rate from color fundus photographs in patients with mild NPDR. [more info]
• Nunes S., Bernardes R., Lobo C., Cunha-Vaz J. Validation of a predictive model for diabetic retinopathy progression in type-2 diabetic patients with mild nonproliferative diabetic retinopathy. [more info]
• Rosa A., Pires I., Silva R., Santos AR., Nunes S., Silva MP., Cachulo ML., Faria de Abreu JR., Cunha-Vaz J. Distrofia foveomacular viteliforme do adulto e tomografia de coerência óptica. [more info]
• Nunes S., Pires I., Rosa A., Duarte L., Bernardes R., Cunha-Vaz J. Microaneurysm Turnover Is a Biomarker for Diabetic Retinopathy Progression to Clinically Significant Macular Edema: Findings for Type 2 Diabetics with Nonproliferative Retinopathy. [more info]
• Bernardes R., Nunes S., Pereira I., Torrent T., Rosa A., Coelho D., Cunha-Vaz J. Computer-assisted microaneurysm turnover in the early stages of diabetic retinopathy. [more info]
• Pires I., Duarte L., Nunes S., Pereira I., Bernardes R., Cunha-Vaz J. Microaneurysms Formation Rate as a Predictor of DR Progression to CSME Needing Photocoagulation in Nonproliferative Retinopathy in Diabetes Type 2. [more info]
• Pereira I., Nunes S., Ribeiro M., Bernardes R., Cunha-Vaz J. Risk markers for progression of mild nonproliferative retinopathy to clinically significant macular edema in type 2 diabetic patient. [more info]
• Nunes S., Baptista P., Bernardes R., Cunha-Vaz J. Comparison of retinal thickness measurements obtained by Retinal Thickness Analyzer (RTA II) and Optical Coherence Tomography (Stratus OCT) in healthy subjects. [more info]

Communications

• Nunes S., Santos T., Ribeiro L., Lobo C., Bernardes R., Cunha-Vaz J. Phenotypes of Diabetic Retinopathy Progression to CSME based on Non-Invasive Examinations. [more info]
• Lobo C., Ribeiro L., Bento G., Nunes S., Simoes M., Miranda T., Bernardes R., Faro C., Cunha-Vaz J. Patterns of Progression in Diabetic Retinopathy. Correlation Between Phenotypes and Genotypes. [more info]
• Nunes S., Santos T., Pires I., Lobo C., Bernardes R., Cunha-Vaz J. Cluster Analysis Identification Of Early Diabetic Retinopathy Phenotypes. [more info]
• Nunes S., Bernardes R., Pereira I., Santos T., Soares M., Pires I., Lobo C., Cunha-Vaz J. Validation of a predictive model for diabetic patients with mild nonproliferative diabetic retinopathy [more info]
• Nunes S., Bernardes R., Lobo C., Cunha-Vaz J. Validation of a predictive model for diabetic retinopathy progression in type-2 diabetic patients with mild nonproliferative diabetic retinopathy [more info]
• Nunes S. Optical Coherence Tomography: A General Overview. [more info]
• Nunes S., Bernardes R., Lobo C., Cunha-Vaz J. Validation of a predictive model for diabetic retinopathy progression in type-2 diabetic patients with mild nonproliferative diabetic retinopathy. [more info]
• Bernardes R., Nunes S., Pereira I., Lobo C., Cunha-Vaz J. Semi-automated assessment of microaneurysm formation rate from color fundus photographs in patients with mild NPDR. [more info]
• Bernardes R., Nunes S., Pereira I., Pires I., Duarte L., Cunha-Vaz J. A new method for semi-automated measurements of microaneurysms formation rate form color fundus photographs in diabetic retinopathy. [more info]
• Santos A., Bernardes R., Silva R., Nunes S., Fonseca P., Carvajal-Gonzalez S., Buggage R., Cunha-Vaz J. Alteration of the blood-retinal leakage analysis is a predictor for conversion to wet age-related macular degeneration. [more info]
• Pereira I., Nunes S., Ribeiro M., Duarte L., Santos A., Bernardes R., Cunha-Vaz J. Weak correlation between retinal thickness and BCVA in CSME eyes patients with diabetes type 2. [more info]
• Nunes S., Pereira I., Bernardes R., Pires I., Duarte L., Cunha-Vaz J. A new method for semi-automated measurements of microaneurysms formation rate form color fundus photographs in diabetic retinopathy. [more info]
• Pereira I., Nunes S., Ribeiro M., Bernardes R., Cunha-Vaz J. Risk Markers for Progression of Mild Proliferative Retinopathy to Clinically Significant Macular Edema in Type 2 Diabetic Patients. [more info]
• Nunes S., Bernardes R. Retinal Leakage Analyser. [more info]
• Nunes S., Ribeiro M., Geraldes E., Bernardes R., Cunha-Vaz J. Risk Markers for Progression to Clinically Significant Macular Edema in Mild Nonproliferative Retinopathy in Diabetes Type 2. [more info]
• Bernardes R., Silva R., Nunes S., Fonseca P., Santos A., Carvajal-Gonzalez S., Buggage R., Cunha-Vaz J. Alteration of the Blood-Retinal Barrier Identified by Retinal Leakage Analysis is a Predictor for Conversion to Wet Age-related Macular Degeneration. [more info]
• Silva R., Nunes S., Bernardes R., Fonseca P., Santos A., Carjaval-Gonzalez S., Buggage R., Cunha-Vaz J. Retinal Edema Identified by Optical Coherence Tomography is a Reliable Indicator of Conversion to Wet Age-related Macular Degeneration. [more info]
• Santos A., Nunes S., Silva M., Bernardes R., Pereira I., Cunha-Vaz J. Correlation Between Central Macular Thickness, Measured by Spectral Domain OCT, Microperimetry, and Visual Acuity Loss in Type 2 Diabetic Patients with Macular Edema. [more info]
• Nunes S. Identification of different phenotypes of nonproliferative retinopathy (NPDR) of diabetes type 2 using Cluster and Discriminant Analysis. [more info]
• Nunes S. Modelo Predictivo de Coimbra – Edema Macular Diabético. [more info]
• Nunes S., Figueira J., Rosa A., Faria de Abreu J., Cunha-Vaz J. Subthreshold Diode Laser Photocoagulation compares favourably with Argon Laser as treatment for mild Clinically Significant Diabetic Macular Edema. [more info]
• Baptista P., Nunes S., Figueira J., Bernardes R., Cunha-Vaz J. Correlation between Central Macular Thickness and Visual Acuity loss in type 2 diabetic patients with Macular Edema. [more info]
• Nunes S., Bernardes R., Duarte L., Cunha-Vaz J. Identification of different phenotypes of mild non-proliferative retinopathy of type 2 diabetes using mathematical analysis. [more info]
• Nunes S., Bernardes R., Duarte L., Cunha-Vaz J. Identification of different phenotypes of nonproliferative retinopathy of diabetes type 2 using cluster and discriminant analysis. [more info]
• Baptista P., Santos T., Nunes S., Bernardes R., Cunha-Vaz J. Establishment of a normative database by registration of RTA maps into the RT-Atlas. [more info]
• Nunes S., Bernardes R., Duarte L., Cunha-Vaz J. Identification of different phenotypes of mild non-proliferative retinopathy of type 2 diabetes using cluster and discriminant mathematical analysis. [more info]
• Duarte L., Ribeiro M., Nunes S., Lobo C., Bernardes R., Geraldes E., Faria de Abreu J., Cunha-Vaz J. A two-year prospective study of mild nonproliferative retinopathy in subjects with diabetes type 2 undergoing intensive oral tritheraphy. Progression of retinopathy under stabilized metabolic control. [more info]
• Nunes S., Figueira J., Bernardes R., Cunha-Vaz J. Mild CSME measured by RTA I and OCT II. Correlation with fundus photography. [more info]
• Nunes S., Bernardes R., Baptista P., Cunha-Vaz J. Retinal thickness measurements: RTA II vs OCT in Healthy Subjects. [more info]
• Nunes S., Figueira J., Bernardes R., Cunha-Vaz J. Mild CSME measured by RTA I and OCT II. Correlation with fundus photography. [more info]
• Duarte L., Figueira J., Nunes S., Bernardes R., Geraldes E., Cunha-Vaz J. Intensified multifactorial intervention in patients with type 2 diabetes mellitus: phenotypes of retinopathy progression. [more info]
• Azevedo H., Duarte L., Nunes S., Bernardes R., Lobo C., Figueira J., Cunha-Vaz J. Patterns of retinopathy progression in a five-year follow-up of mild nonproliferative retinopathy in diabetes type 2. Development of clinically significant macular edema. [more info]
• Bernardes R., Nunes S., Duarte L., Cunha-Vaz J. Comparison between retinal edema by color fundus photography and retinal thickness maps. [more info]
• Nunes S., Bernardes R., Baptista P., Cunha-Vaz J. Retinal Thickness Measurements: RTA II vs Stratus OCT in Healthy Subjects. [more info]
• Nunes S., Bernardes R., Torrent-Solans T., Soares M., Cunha-Vaz J. Retinal thickness measurements: RTA I vs RTA II, OCT II vs Stratus OCT and RTA II vs Stratus OCT in normal eyes. [more info]
• Bernardes R., Nunes S., Varandas J., Lobo C., Cunha-Vaz J. Detailed Retinal Thickness Mapping Using the Stratus OCT. [more info]
• Nunes S., Bernardes R., Lobo C., Cunha-Vaz J. The Retina Thickness Analyzer as a tool to evaluate drug efficacy in nonproliferative retinopathy in type 2 diabetic subjects. [more info]
• Nunes S., Monteiro R., Bernardes R., Torrent-Solans T., Duarte L., Cunha-Vaz J. Computer assisted microaneurysms counting on digitized retinographies. [more info]
• Nunes S., Bernardes R., Torrent-Solans T., Cunha-Vaz J. Retinal thickness measurements: RTA I vs RTA II, OCT II vs Stratus OCT and RTA II vs Stratus OCT in normal eyes. [more info]
• Nunes S., Bernardes R., Torrent-Solans T., Soares M., Cunha-Vaz J. Retinal thickness measurements: RTA I vs RTA II, OCT II vs Stratus OCT and RTA II vs Stratus OCT in normal eyes. [more info]
• Bernardes R., Nunes S., Varandas J., Lobo C., Cunha-Vaz J. Detailed Retinal Thickness Mapping Using the Stratus OCT. [more info]
• Nunes S., Bernardes R., Torrent-Solans T., Soares M., Cunha-Vaz J. The retinal thickness analyzer as a tool to evaluate drug efficacy in nonproliferative retinopathy in type 2 diabetes subjects. [more info]
• Bernardes R., Monteiro R., Nunes S., Cunha-Vaz J. OCT Increased Resolution Retinal Thickness Mapping. [more info]
• Nunes S., Monteiro R., Bernardes R., Torrent-Solans T., Duarte L., Cunha-Vaz J. Computer-assisted microaneurysms counting on Digitized retinographies. [more info]
• Monteiro R., Bernardes R., Nunes S., Cunha-Vaz J. Retinal thickness mapping using the optical coherence tomograph with increased sampling. [more info]
• Torrent-Solans T., Monteiro R., Nunes S., Bernardes R., Cunha-Vaz J. Microaneurysms counting on digitized fundus images. [more info]
• Nunes S., Monteiro R., Bernardes R., Torrent-Solans T., Duarte L., Cunha-Vaz J. Computer-assisted microaneurysms counting on digitized retinographies. [more info]
• Monteiro R., Bernardes R., Nunes S., Cunha-Vaz J. Increased retinal thickness mapping using optical coherence tomograph. [more info]
• Bernardes R., Monteiro R., Nunes S., Cunha-Vaz J. Inner limiting membrane and retinal pigment epithelium detection on optical coherence tomograph. [more info]