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4C // Coimbra Coordinating Centre for Clinical Research


Prospective, randomized, open label phase II study to assess efficacy and safety of Macugen® (pegaptanib 0.3 mg intravitreal injections) plus panretinal photocoagulation (PRP) and PRP (monotherapy) in the treatment of patients with high risk proliferative diabetic retinopathy [more info]

Prospective, randomized, multicenter, open label phase II study to access efficacy and safety of Lucentis® monotherapy (ranibizumab 0.5 mg intravitreal injections) compared with Lucentis® plus panretinal photocoagulation (PRP) and PRP (monotherapy) in the treatment of patients with high risk proliferative diabetic retinopathy [more info]

Epidemiological study of the prevalence of Age-Related Macular Degeneration in Portugal [more info]

Services

  • Protocol Design and Statistical Planning
  • Elaboration of the necessary documents for the submission of the clinical trial
  • Submission to the Regulatory Authorities
  • Coordination and implementation of the clinical trial
  • Monitoring
  • Quality Control
  • Data management
  • Statistical analysis
  • Periodical reports to the Sponsor and/or Regulatory Authorities
  • Final clinical trial report
  • Publication support
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